Avaforce 50 mg, which contains Avanafil, is a medication used to treat erectile dysfunction (ED) by increasing blood flow to the penis. Like other PDE5 inhibitors (e.g., Sildenafil and Tadalafil), Avanafil works by blocking the PDE5 enzyme, leading to increased cyclic GMP levels and enhanced blood circulation.
Eye Color Changes:
One of the rare side effects of PDE5 inhibitors, including Avaforce 50 mg, is a condition known as cyanopsia, which causes blue-tinted vision or changes in color perception. This side effect occurs because PDE5 inhibitors, while primarily acting on the penile blood vessels, can also have an impact on the retina of the eye.
In particular, PDE5 inhibitors can affect the enzyme PDE6, which is present in the retina and is responsible for converting light signals into visual information. When PDE6 is inhibited, it can cause alterations in color vision, leading to a blueish tint or even difficulty distinguishing between certain colors (like blue and green).
Why It Happens:
This effect is thought to be due to the similarity between PDE5 and PDE6 enzymes, which are found in both the penis and the eyes. However, this side effect is usually temporary and tends to resolve once the drug is out of the system.
When to Seek Help:
If you experience persistent or severe vision changes, it’s important to contact your healthcare provider, as this could indicate a more serious issue.