Vigora 100mg is a medication used to treat erectile dysfunction (ED) in men. The active ingredient in Vigora 100mg is sildenafil citrate, which belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors.
Here’s how it works:
Relaxation of Blood Vessels: During sexual arousal, the body releases nitric oxide in the erectile tissue of the penis. Nitric oxide then activates an enzyme called guanylate cyclase, which results in an increase in levels of cyclic guanosine monophosphate (cGMP). This, in turn, causes the smooth muscle of the blood vessels in the penis to relax.
Increased Blood Flow: Relaxation of the smooth muscle allows an increased flow of blood into certain areas of the penis, leading to an erection. The increased blood flow is crucial for achieving and maintaining an erection.
PDE5 Inhibition: However, another enzyme called phosphodiesterase type 5 (PDE5) can break down cGMP, reducing its levels and reversing the effects of nitric oxide. Sildenafil, the active ingredient in Vigora 100mg, inhibits PDE5. By doing so, it helps to maintain higher levels of cGMP, prolonging the relaxation of the smooth muscle and allowing for a sustained erection.
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